Journal: bioRxiv

Article Title: Spatial transcriptomics implicates the thalamus and cortex in autism and schizophrenia

doi: 10.64898/2026.05.15.724759

Figure Lengend Snippet: a) Serial sagittal adult mouse brain sections were collected onto 10x Visium capture areas, which extracted RNA onto spatially barcoded spots. Tissue sections were segmented by atlas registration to identify clusters and enriched regions. b) Tissue samples from 16 sections in four mouse brains (rows) by serial slice (column) from lateral (left) to medial (right). Registered anatomical boundaries are overlaid and labelled. c) Corresponding slice positions represented in the coronal plane (left) and magnified for relative positioning (right).

Article Snippet: Spatial transcriptomics analysis was performed using the 10x Genomics Visium Spatial Gene Expression Assay.

Techniques:

Journal: bioRxiv

Article Title: Spatial transcriptomics implicates the thalamus and cortex in autism and schizophrenia

doi: 10.64898/2026.05.15.724759

Figure Lengend Snippet: a) Serial sagittal adult mouse brain sections were collected onto 10x Visium capture areas, which extracted RNA onto spatially barcoded spots. Tissue sections were segmented by atlas registration to identify clusters and enriched regions. b) Tissue samples from 16 sections in four mouse brains (rows) by serial slice (column) from lateral (left) to medial (right). Registered anatomical boundaries are overlaid and labelled. c) Corresponding slice positions represented in the coronal plane (left) and magnified for relative positioning (right).

Article Snippet: We mounted 4 such sections from 1 brain on a Visium Spatial Gene Expression Slide (10x Genomics, 1000187) and stored at -80°C until further processing.

Techniques: